Trimethoprim 200mg for Women

Trimethoprim is an antibiotic commonly used to treat cystitis (urinary tract infections) in women. It works by stopping the growth of bacteria that cause infections in the urinary tract. While it remains a widely used treatment, some bacteria have developed resistance to trimethoprim, making nitrofurantoin a more commonly recommended option in certain cases.

Trimethoprim prevents bacteria from multiplying by interfering with their ability to produce folate, an essential component for bacterial growth. By halting their ability to reproduce, the immune system can effectively clear the infection, leading to symptom relief and recovery.

• The usual dosage for treating cystitis is 200mg twice daily for 3 days.
• Doses should be taken 12 hours apart to ensure consistent antibiotic levels in the body.
• Swallow tablets whole with a glass of water—do not chew or crush them.
• Most people experience an improvement within 24 hours, but it’s important to complete the full course, even if symptoms resolve earlier.

Like all medicines, trimethoprim may cause side effects, although not everyone will experience them.

Common Side Effects (May Affect up to 1 in 10 People):

• Feeling nauseous or being sick
• Diarrhoea
• Headaches
• Skin rashes or itching
• Oral thrush or a sore mouth

Rare but Serious Side Effects (Seek Medical Attention Immediately):

• Severe allergic reactions – swelling of the lips, throat, or face (angioedema), difficulty breathing
• Severe skin reactions – blistering, peeling, or a widespread rash
• Signs of anaemia – extreme tiredness, pale skin, shortness of breath

Do not take trimethoprim if you:

• Are allergic to trimethoprim or any of its ingredients.
• Are pregnant (as it may interfere with folate levels in the baby).
• Have serious liver disease.

Consult a doctor before taking trimethoprim if you:

• Have kidney disease or are on dialysis.
• Have low folic acid levels, as this could lead to anaemia.
• Have a history of high potassium levels.
• Are taking medications that may interact with trimethoprim, such as warfarin, phenytoin, rifampicin, or diuretics.

If symptoms persist or worsen, or if new symptoms develop, seek medical advice promptly.