Wegovy vs Saxenda: Difference You Must Know

January 04, 2024

Wegovy vs Saxenda: Difference You Must Know

Wegovy and Saxenda are both potential weight-loss medications. Considering the availability, the question arises: which one is the best? Since both help to overcome the obesity problem and maintain a healthy weight, making informed decisions between the two becomes a daunting task.

In this detailed article, we will discuss Wegovy vs Saxenda, starting from its efficacy to its mechanism of action, side effects, and dosage options. So, stay tuned and pick the right product for your weight loss journey.

Wegovy vs Saxenda





1. Active Ingredients



2. Mechanism of Action

GLP-1 receptor agonist

GLP-1 receptor agonist

3. Duration of Action

Approximately seven days (weekly injection)

About 24 hours (daily injection)

4. Average Weight Loss in Trials



5. Dosage

Starting with 0.25mg to a maximum of 2.4mg weekly injections

Beginning with 0.6mg to a maximum of 3 mg weekly injections

6. Target Volunteers

Obese or overweight individuals with weight-related health conditions seek maximal weight loss.

Obese or overweight individuals are potentially cost-sensitive or require a shorter-term intervention.

7. Costing



8. Benefits

Superior efficacy, improved side-effect profile, more straightforward dosing schedule

Lower cost, the potential for faster initial weight loss

9. Side Effects

Nausea, vomiting, diarrhea (generally less frequent and severe than Saxenda)

Nausea, vomiting, diarrhea, constipation, injection site reactions


Similarities: Wegovy vs Saxenda

  • Both wegovy weight loss injections and Saxenda make you feel fuller and keep you away from food.

  • Both are FDA-approved to improve health and keep your weight under control.

  • Both are injections, minimally invasive

  • Both cause common side effects, including nausea, vomiting, and diarrhea.

Differences: Wegovy vs Saxenda

  • While Saxenda uses Liraglutide as an active ingredient, its competitor uses Semaglutide to cut down excessive pounds from its consumer.

  • Considering Wegovy’s potential, it is advisable to inject it weekly, while Saxenda users require it to be injected daily.

  • Wegovy works for about a week, while Saxenda works only 24 hours.

  • Wegovy is more effective than Saxenda for cutting down unnecessary pounds from the body.

  • Wegovy is quite safer than Saxenda, which has several side effects. 


While Wegovy and Saxenda are powerful weight-loss injections, emerging data suggests Wegovy could be the more potent long-term option. Studies indicate it leads to greater weight loss and potentially carries a lower side-effect profile. With this in mind, Novo Nordisk, the manufacturer, intends to eventually shift focus entirely to Wegovy.