Imigran Nasal Spray

Imigran Nasal Spray is a prescription medication developed for treating acute migraine episodes. Migraines differ significantly from regular headaches, causing intense throbbing pain, often accompanied by sensitivity to environmental stimuli and nausea. While the exact causes of migraines remain unclear, various triggers have been identified including dietary factors (such as aged cheese, dark chocolate, and red wine), emotional states (like stress), and physical conditions (including fatigue and hunger).

The active component in Imigran Nasal Spray, sumatriptan, works to constrict the dilated blood vessels in the brain that are responsible for migraine pain. By narrowing these expanded vessels, sumatriptan helps alleviate the painful symptoms associated with migraines. The nasal spray should be used at the first indication of a migraine or at any point during an attack. It is important to note that Imigran Nasal Spray is not intended for preventative use or pre-emptive administration before a migraine occurs.

Imigran Nasal Spray is supplied in single-dose units containing either 10mg or 20mg of sumatriptan. The device has three main components: a nasal nozzle for insertion, a finger-grip area, and a blue plunger that delivers the medicine.

Administration steps:

1. Clear your nasal passages if blocked
2. Insert the nozzle into one nostril
3. Block the opposite nostril with your finger
4. Tilt your head back slightly and close your mouth
5. Begin to inhale gently through your nose
6. Whilst inhaling, press the plunger firmly to release the full dose
7. Remove the device and dispose of it properly

Normal reactions include a slight wetness in the nose and a distinctive taste sensation in the mouth following administration.

Dosage guidelines:

• Adults (18-65 years): One spray of 10-20mg in a single nostril
• Adolescents (12-17 years): One spray of 10-20mg in a single nostril
• Maximum daily dosage: Two 20mg sprays within a 24-hour period
• Not recommended for children under 12 or adults over 65 years

Using Imigran Nasal Spray may cause various reactions:

Very frequently observed effects (affecting more than 1 in 10 users):

• Unusual or unpleasant taste sensations in the throat
• Nosebleed

Commonly observed effects (affecting up to 1 in 10 users):

• Sensation of pressure or discomfort in the throat, chest, or other body regions
• Unusual sensations including numbness or temperature changes (hot/cold) in various body parts

Extremely rare effects (affecting up to 1 in 1,000 users):

• Alterations in liver function parameters (may be detected through blood tests)

If chest pain or other severe symptoms persist, seek immediate medical attention as these could potentially indicate serious complications in rare cases.

Certain individuals should avoid using Imigran Nasal Spray, particularly those who:

• Have hypersensitivity to any ingredients in the formulation
• Have cardiac conditions including ischaemic heart disease, angina, or previous heart attack
• Have experienced stroke or transient ischaemic attack (mini-stroke)
• Have severe hepatic (liver) impairment
• Experience uncontrolled hypertension
• Are currently using other migraine medicines containing ergotamine, methysergide, or other triptans

Special care is necessary if you:

• Smoke heavily
• Have a history of seizure disorders
• Have impaired kidney or liver function
• Are taking SSRI antidepressant medicines

Medicine Interactions: Inform your GP or pharmacist about all medicines you're taking, especially:

• Other migraine treatments (particularly triptans or ergotamine-containing medicines)
• Antidepressants (including SSRIs, SNRIs, and MAOIs)
• Herbal supplements such as St John's Wort

Pregnancy and Breastfeeding: Consult your GP before using Imigran if pregnant or planning pregnancy. After using the spray, breastfeeding should be avoided for 12 hours.