Varenicline (Champix)

Varenicline is a nicotine receptor agonist that interacts with receptors in the brain. It mimics the effects of nicotine at a lower intensity while simultaneously preventing nicotine from binding. This helps to reduce cravings, ease withdrawal symptoms, and make smoking less pleasurable, discouraging relapse.

• Begin treatment 1–2 weeks before your planned quit date.
• Follow this dosage schedule:
  • Days 1–3: Take 0.5mg once per day (white tablet).
  • Days 4–7: Increase to 0.5mg twice daily (white tablet).
  • Day 8 onwards: Take 1mg twice daily (light blue tablet).
• The full course lasts 12 weeks, with an additional 12-week maintenance course recommended for those who successfully quit.
• Tablets should be taken at the same time each day, with or without food. If a dose is missed, do not take extra tablets to compensate.

Yes. Unlike nicotine patches, gum, or lozenges, Varenicline does not contain nicotine. Instead, it works by blocking nicotine’s effects, helping to reduce dependence without reinforcing addiction.

While most users tolerate Varenicline well, some may experience:

• Nausea or an upset stomach
• Dizziness or headaches
• Sleep disturbances, including vivid dreams
• Changes in appetite
• Drowsiness

Taking the tablets with food can help minimise the risk of nausea and abnormal dreams. If any side effects persist or become bothersome, consult a doctor or pharmacist.

• Not suitable for individuals with an allergy to Varenicline or any of its ingredients.
• If you experience mood changes, agitation, or unusual thoughts, seek medical advice.
• Smoking while taking Varenicline is not advised, as it can still lead to relapse.
• Setting a firm quit date before starting treatment improves success rates.